Research Projects


Medication monitoring for people with dementia in care homes: a pre-pilot before and after study

Research team

Sue Jordan, Swansea University (PI)
Marie Gabe (researcher) BN., BSc., RN.
Sherrill Snelgrove PhD, M.Phil, BSc, RGN, lecturer in psychology applied to nursing
Gerwyn Panes RMN., MSc., BSc., LPE (PGCE). Co-ordinator BN nursing mental health
Ian Russell, Professor of Clinical Trials, Director WWORTH
Peter Huxley, Professor of Social Work; Director MHRNC
Mick Dennis, Professor of Liaison and Old Age Psychiatry
Ceri Phillips, Professor of Health Economics


Older adults with dementia are vulnerable to the well known adverse effects of medicines prescribed for mental health problems. However, they are rarely monitored for possible adverse reactions to their medicines.

To explore the introduction of a structure nurse-led medication monitoring profile.

This pre-pilot ‘before and after’ study explored the operation of and any preliminary clinical gains from medication monitoring in homes caring for service users with dementia.

Participants and setting
11 patients diagnosed with dementia taking at least one of: antipsychotics, antidepressants or anti-epileptics in 3 care homes in SW Wales.

Care home nurses were asked to seek consent of patients’ next of kin and complete the ADR profile during usual care and contact with patients. This involved observing or questioning patients and seeking information from patients’ records. Researchers transcribed information from the completed profiles and extracted data from patients’ case notes to: a) seek evidence of previous medication monitoring b) ascertain whether information on the ADR profile had already been captured c) what actions were planned following administration of the ADR profile. Findings were described using IBM SPSS v.19

The profile identified previously undocumented problems for all patients: mean 12.7 [4.7], range 8-21. Some problems, such as posture and movement disorders, postural hypotension and fluid intake were monitored for the first time. New problems identified and actioned included: pain (2 patients), abnormal movements (4 patients), postural hypotension (2 patients). Nurses indicated that they intended to improve liaison with dentists and increase oral care. Not all problems identified were actioned: mean number of actions 3.0, -0.6-6.6 possibly because the nurses were aware of the problems, even if undocumented. The profile took 20-25 minutes to implement, caused no harm, and was seen as comprehensive.

The profile improved the process of care, but longer-term follow up is needed to demonstrate an effect on clinical outcomes. Patients are likely to benefit from structured nurse-led medication monitoring, but without a full clinical trial, profiles are unlikely to be widely adopted in routine care.

Start / end dates

December 2011-February 2013

Related links

Jordan S, Gabe M, Newson L, Snelgrove S, Panes G, Picek A, Russell IT, Dennis M. (2014) "Medication Monitoring for People with Dementia in Care Homes:  the Feasibility and Clinical Impact of Nurse-led monitoring," The Scientific World Journal, vol. 2014, Article ID 843621, 2014. doi:10.1155/2014/843621.


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